Intravenous Iron Administration and Hypophosphatemia in Clinical Practice

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Intravenous Iron Administration and Hypophosphatemia in Clinical Practice

Introduction. Parenteral iron formulations are frequently used to correct iron deficiency anemia (IDA) and iron deficiency (ID). Intravenous formulation efficacy on ferritin and hemoglobin level improvement is greater than that of oral formulations while they are associated with lower gastrointestinal side effects. Ferric carboxymaltose- (FCM-) related hypophosphatemia is frequent and appears w...

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Clinical use of intravenous iron: administration, efficacy, and safety.

This section reviews the history, pharmacology, administration, efficacy, and toxicity of intravenous iron. Intravenous iron offers advantages over oral iron for the treatment of iron deficiency anemia across a wide range of disease states associated with absolute and functional iron deficiency. However, there remain concerns about the acute safety profiles of the available preparations and the...

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Choice of High-Dose Intravenous Iron Preparation Determines Hypophosphatemia Risk

BACKGROUND Ferric carboxymaltose (FCM) and iron isomaltoside 1000 (IIM) are increasingly used because they allow correction of severe iron deficiency in a single infusion. A transient decrease in serum phosphate concentrations is a frequent side effect of FCM. AIM To characterize this adverse event and search for its predictors in a gastroenterology clinic patient cohort. METHODS Electronic...

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Severe hypophosphataemia after intravenous iron administration

Currently, in many centres, intravenous administration of iron is becoming increasingly popular because of higher efficacy and decreased side effects, mainly gastrointestinal, compared with oral iron therapy. Studies of intravenous ferric carboxymaltose administration in the postpartum setting and in patients with non-dialysis-dependent chronic kidney disease revealed a decrease in serum phosph...

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Safety and Efficacy of Intravenous Administration of Iron Preparations.

Iron deficiency is the main cause of anemia worldwide. Iron supplementation leads to a rise of transferrin saturation and ferritin concentration, resulting in an increased hemoglobin level and decrease of anemia symptoms. Oral iron administration is a treatment of choice in iron deficiency anemia. In patients with impaired iron absorption from the gastrointestinal tract, as well as in large def...

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ژورنال

عنوان ژورنال: International Journal of Rheumatology

سال: 2015

ISSN: 1687-9260,1687-9279

DOI: 10.1155/2015/468675